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Question

Choose the vector which is used in gene mapping.

A
Plasmid vector
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B
Phage vector
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C
Cosmid vector
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D
Yeast artificial chromosome (YAC)
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Solution

The correct option is D Yeast artificial chromosome (YAC)
Yeast artificial chromosome (YAC) is used in gene mapping because larger size of foreign DNA (around 1 Mb) can be inserted in YAC.

All the other options have a smaller insert size and hence cannot be used. Plasmids can hold upto 7 kb, the insert size of a phage vector is upto 11 kb and for a cosmid vector it is upto 45 kb.

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