The correct option is C lose
The word 'acquire' refers to buying or obtaining an asset or object for oneself.
Option A, lose refers to failing to win a game or contest.
Option B, deprive refers to preventing a person from having or using something.
Option C, forsake refers to abandoning or leaving something.
Option D, surrender refers to giving up or handing over something.
Thus, according to the meaning, the word 'acquire' is the opposite of the word 'lose'.