The correct option is A unsympathetic
The word 'humane' refers to having or showing compassion or benevolence.
Option A, unsympathetic refers to not feeling, expressing or showing sympathy.
Option B, uncultured refers to not characterized by good taste, manner or education.
Option C, uncompromising refers to being unbending and inflexible.
Option D, uncivilised refers to not being socially, culturally or morally advanced.
Thus, according to the meaning, the word 'unsympathetic' is the opposite of the word 'humane'.