The correct option is A fact
The word 'hypothesis' refers to a proposition made on the basis of reasoning, without any assumption of its truth.
Option A, fact refers to a thing that is known or proved to be true.
Option B, theory refers to a set of principles on which the practice is based on.
Option C, conclusion refers to the end or finish of an event, process or text.
Option D, experiment refers to a test or investigation.
Thus, according to the meaning, the word 'fact' is the opposite of the word 'hypothesis'.