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Question
Choose the wrong statement regarding AIDS.
Choose the wrong statement regarding AIDS.
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Solution
The correct option is C HIV selectively infects and kills B-lymphocytes
AIDS :
AIDS stands for Acquired Immuno Deficiency Syndrome, caused by the Human Immunodeficiency Virus (HIV). HIV infects and destroys helper T-lymphocytes and macrophages in the human body which weakens the immune system.
Statement (a) :
It is an immunodeficiency disease.
Elaboration : AIDS is an immunodeficiency disease in which the immune system of the patient is hampered as the HIV infects and destroys helper T-lymphocytes and macrophages in the human body. Hence the given statement in option (a) is true.
Statement (b) :
It is caused by retrovirus HIV.
Elaboration : HIV (Human Immuno deficiency Virus) is a retrovirus which contains two single stranded RNAs and reverse transcriptase enzymes. Hence the given statement in option (b) is true.
Statement (c) :
HIV selectively infects and kills B-lymphocytes.
Elaboration : HIV infects and destroys helper T-lymphocytes and macrophages in the human body which weakens the immune system. Hence the given statement in option (c) is wrong.
Statement (d) :
Genome RNA replicates via DNA intermediate.
Elaboration : HIV has a reverse transcriptase enzyme associated with the RNA genome, which converts viral RNA to DNA through reverse transcription. The viral DNA gets integrated into the host genome and directs the host cell to assist the formation of viral RNA molecules that helps in forming viral proteins using host ribosomes. The transcribed genomic RNA and viral proteins are assembled to form viral particles. Hence the given statement in option (d) is true.
Final answer :
(c) HIV selectively infects and kills B-lymphocytes
AIDS :
AIDS stands for Acquired Immuno Deficiency Syndrome, caused by the Human Immunodeficiency Virus (HIV). HIV infects and destroys helper T-lymphocytes and macrophages in the human body which weakens the immune system.
Statement (a) :
It is an immunodeficiency disease.
Elaboration : AIDS is an immunodeficiency disease in which the immune system of the patient is hampered as the HIV infects and destroys helper T-lymphocytes and macrophages in the human body. Hence the given statement in option (a) is true.
Statement (b) :
It is caused by retrovirus HIV.
Elaboration : HIV (Human Immuno deficiency Virus) is a retrovirus which contains two single stranded RNAs and reverse transcriptase enzymes. Hence the given statement in option (b) is true.
Statement (c) :
HIV selectively infects and kills B-lymphocytes.
Elaboration : HIV infects and destroys helper T-lymphocytes and macrophages in the human body which weakens the immune system. Hence the given statement in option (c) is wrong.
Statement (d) :
Genome RNA replicates via DNA intermediate.
Elaboration : HIV has a reverse transcriptase enzyme associated with the RNA genome, which converts viral RNA to DNA through reverse transcription. The viral DNA gets integrated into the host genome and directs the host cell to assist the formation of viral RNA molecules that helps in forming viral proteins using host ribosomes. The transcribed genomic RNA and viral proteins are assembled to form viral particles. Hence the given statement in option (d) is true.
Final answer :
(c) HIV selectively infects and kills B-lymphocytes
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