Question

Clumping of RBC may occur when blood of one person is mixed with serum or blood of another person. This is due to

• A. Antigen-antibody reaction
• B. Antitoxin-antibody reaction
• C. Antigen-antigen reaction
• D. Antibody-antibody reaction

Answer 1

The correct option is A Antigen-antibody reaction

The RBC membrane contains either antigen A or antigen B, or both Antigen A and B or no antigen at all, accordingly the blood is classified as blood group A , B , AB and O respectively. The blood plasma of blood group A will have antibodies for B, that of B will have antibodies for A, that of AB will have non, while that of O will have both the antibodies. If blood is transfused at random this will lead to antigen-antibody reaction - like if A is the blood group of the recipient while the blood group of the donor happens to be B, this will lead to clumping of the RBCs.

So, the correct answer is 'Antigen-antibody reaction'