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Question

Colchicine arrests mitosis at

A
Prophase
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B
Metaphase
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C
Anaphase
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D
Interphase
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Solution

The correct option is A Prophase
Colchicine is an alkaloid drug that is considered to be a cellular poison. It stops the cell division and arrests the cells at the metaphase stage. It generally works by destructing the spindle fibre formation which results in the separation of the chromosome. Thus chromosome cannot separate during the anaphase and they are stuck at the metaphase stage.
Therefore B is the correct option.

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