Colchicine interferes with

Chromosome replication

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Organisation of spindle

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Chromosome condensation

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Incorporation of nitrogen bases

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Solution

The correct option is B Organisation of spindle
Alkaloid colchicine (produced by many plants of family Liliaceae) inhibits the microtubules to assemble to form spindle fibres. Therefore, alkaloid colchicine interferes with mitosis and chromosome segregation and the cell division is arrested at metaphase in presence of colchicine.

So, the correct answer is 'Organisation of spindle'.

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