Question

Colchicine is a

• A. Mitotic poison
• B. Cytokinesis poison
• C. Prophase poison
• D. None of the above

Answer 1

The correct option is A Mitotic poison

Colchicine is believed to interfere with cell division through its disruptive action on the mitotic spindle. Direct evidence for this has been obtained from polarized light microscopy and from isolation of the remnants of the mitotic apparatus of colchicine-treated sea urchin eggs. Colchicine breaks down microtubules which pull apart the chromosomes and other cell parts in mitosis. So, it stops the cells from completing mitosis.