Resting Potential | Action Potential |
1. It is potential difference across the membrane when neuron is resting. | It is a potential differenceacross the membrane when the neuron is stimulated. |
2. At resting potenial, a nerve fibre is not conducting an impulse. Although both the Na+ and K+ channels remained closed during resting potential, yet the membrane of the neuron is moderately permeable to Na+ and quite (50 to 100 times more) permeable to K+ and Cl− ions | During action potential, the neuron membrane is more permeable to sodium due to opening of Na+ channels. The K+, channels remained closed. |
3. In resting potential the interior of neuron is electronegative and the exterior is electropositive | In action potential the interior of neuron is electropositive and the exterior is electronegative potassium. |
4. An active sodium potassium pump operates. | No sodium pump is operating. |