Compared to the resting state, vigorously contracting skeletal muscle exhibits

an increased conversion of pyruvate to lactate

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decreased oxidation of pyruvate to carbon dioxide and water

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decreased NADH/NAD+ ratio

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decreased concentration of AMP

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Solution

The correct option is A an increased conversion of pyruvate to lactate
Vigorously contracting muscle shows an increased formation of lactate and an increased rate of pyruvate oxidation compared with resting skeletal muscle. This is due to limited availabilty of oxygen to carry out oxidative phosphorylation.

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According to the sliding filament mechanism of skeletal-muscle contraction, during contraction:

C a^{2 +}

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