Complete the following sentence by selecting the correct option. The breathing rhythm is generated in the __(i)__ and is influenced by variation in levels of __(ii)___ in the blood.
A
(i)medulla
(ii)CO2
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B
(i)medulla
(ii)O2
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C
(i)frontal lobe
(ii)CO2 and O2
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D
(i)frontal lobe
(ii)CO2
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Solution
The correct option is A (i)medulla
(ii)CO2
The basic rhythm of respiration is generated mainly in the dorsal respiratory group in the medulla. Changes in blood carbon dioxide are believed to stimulate the neurons in the chemosensitive area which affect the rhythm centre. CO2 acts by forming carbonic acid which dissociates into H+and HCO−3. H+ has a direct effect on this. Oxygen does not have a significant direct effect on rhythm centre.