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Question

Conn's disease is caused by the over-secretion of

A
ADH
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B
ACTH
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C
Aldosterone
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D
Oxytocin
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Solution

The correct option is B Aldosterone
Secretion of large amounts of aldosterone results in Conn's syndrome also called primary aldosteronism. Tumor in the zona glomerulosa cells of the adrenal cortex leads to hypersecretion of aldosterone. Adrenocortical hyperplasia (increase in the amount of tissue due to excessive cell proliferation) is another reason for excessive production. Symptoms associated with the condition include; Hypokalemia (low potassium levels in blood and tissue fluids) may lead to muscle paralysis. Hypertension (increased blood pressure).

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