Question

Consider the following statements:
(A) Co-enzyme or metal ion that is tightly bound to enzyme protein is called prosthetic group
(B) A complete catalytic active enzyme with its bound prosthetic group is called apoenzyme.

Select the correct option.

• A. (A) is false but (B) is true
• B. Both (A) and (B) are true
• C. (A) is true but (B) is false
• D. Both (A) and (B) are false

Answer 1

The correct option is D Both (A) and (B) are false

An enzyme consists of a protein part (apoenzyme) and a non-protein part (cofactor).

The apoenzyme and cofactor together form the holoenzyme.

There are three kinds of cofactors - prosthetic groups, co-enzymes and metal ions.

The organic co-factor includes the prosthetic group and coenzymes while metal ions are inorganic cofactors.

The association of co-enzymes with apoenzymes is transient. However, the prosthetic groups are tightly bound to the apoenzyme.