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Coagulation Cascade

Consider the ...

Question

Consider the given statements and select the option that correctly states them as true (T) or false (F).

A. Long exposure to harmful substances, gases, fumes and dust produced in certain industries can give rise to inflammation in lungs leading to fibrosis.

B. When percentage saturation of haemoglobin with $O_{2}$ is plotted against $p O_{2}$ , the curve obtained is described as hyperbola.

C. Presence of low levels of $H C O_{3}^{-}$ ions and high levels of $O_{2}$ can activate the chemosensitive area present adjacent to rhythm centre.

D. Skin is not a respiratory organ in humans.

A

A - T, B - T, C - F, D - T

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B

A - T, B - F, C - F, D - T

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C

A - T, B - T, C - T, D - T

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D

A - T, B - T, C - T, D - T

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Solution

The correct option is B A - T, B - F, C - F, D - T
The relationship between partial pressure of oxygen and percentage saturation of the haemoglobin with oxygen is graphically illustrated by a curve called oxygen haemoglobin dissociation curve. Under normal conditions the oxygen haemoglobin dissociation curve is sigmoid or s-shaped.

A chemosensitive area is situated adjacent to the rhythm centre which is highly sensitive to CO2 and hydrogen ions. The increase in these substances can activate this centre, which in turn can signal the rhythm centre to make necessary adjustments in the respiratory process by which these substances can be eliminated.

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Similar questions

Q. Consider the given statements and select the option that correctly states them as true(T) or false(F).
a. Increased asthmatic attacks in certain seasons are related to inhalation of seasonal pollen.

b. The part of brain where vomit centre is present, also regulates the respiratory rhythm according to the need of the body.

c. Cigarette smoking causes inflammation of trachea and bronchi.

d. Expiration is initiated due to contraction of diaphragm.

Q. Assertion :A sigmoid curve is obtained when percentage saturation of haemoglobin with

O_{2}

is plotted against the P

O_{2}

. Reason: Every 100 mL of oxygenated blood can deliver around 5ml of

O_{2}

to the tissues under normal physiological conditions.

Q. A chemosensitive area is situated adjacent to respiratory rhythm centre, which is highly sensitive to ..... and ..... ions?

Q. In the given figure curve shows percentage saturation of haemoglobin with $O_{2}$ is plottedagainst $p O_{2}$ . This curve is highly useful instudying the effect of which factors on binding of $O_{2}$ with haemoglobin?

Read the following statements and find out the incorrect statement $(s) .$

a .

C O_{2}

with haemoglobin is related to the partial pressure of

C O_{2} . p O_{2}

is a major factor which could affect this binding.

b .

p C O_{2}

p O_{2}

is high as in the alveoli, more binding of

C O_{2}

occurs, whereas when the

p C O_{2}

p O_{2}

is low as in the tissues, dissolution of

C O_{2}

from carbaminohaemoglobin takes place.

c .

At the tissue site, where partial pressure of

C O_{2}

is high due to catabolism,

C O_{2}

diffuses into blood

(R B C s and plasma)

H C O_{3}^{-}

H^{+} .

At the alveolar site where

p C O_{2}

is low, the reaction proceeds in the opposite direction leading to the formation of

C O_{2}

H_{2} O .

$d .$ Oxygen dissociation curve is highly useful in studying the effect of factor like $p C O_{2}, H^{+}$ concentration, etc., on binding of $O_{2}$ with haemoglobin.

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