Question

Consider the Hofmann ammonolysis reaction:

If $R=C_2{H}_5$, the correct order of basic character of the above amines in aqueous medium is :

• A. $2>3>1>N{H}_3$
• B. $2>1>3>N{H}_3$
• C. $3>2>1>N{H}_3$
• D. $N{H}_3>1>2>3$

Answer 1

The correct option is A $2>3>1>N{H}_3$

If $R=C_2{H}_5$, the correct order of basic character of the above amines in aqueous medium is $2>3>1>N{H}_3$. The factors that determine basicity are the +I effect of alkyl groups and the solvation /hydration in aqueous medium.