Question

Consider the Hofmann ammonolysis reaction:

If $R=C{H}_3$, the correct order of basic character of 1 amine, 2 amine, 3 amine, and $N{H}_3$ in aqueous medium is :

• A. $1>2>3>N{H}_3$
• B. $2>3>1>N{H}_3$
• C. $2>1>3>N{H}_3$
• D. $2>1>N{H}_3>3$

Answer 1

The correct option is C $2>1>3>N{H}_3$

If $R=C{H}_3$, the correct order of basic character of 1 amine, 2 amine, 3 amine, and $N{H}_3$ in aqueous medium is $2>1>3>N{H}_3$. The factors that determine basicity are the +I effect of alkyl groups and the solvation /hydration in aqueous medium.