Question

Conversion of glucose 6-P requires ATP. Yet critically ill patients are given glucose solution intravenously instead of glucose 6-P. The reason for not giving glucose 6-P directly is

• A. Glucose 6-P is degraded very fast in the blood before it enters the cells
• B. Commercial preparation of glucose 6-P is always contaminated with toxic chemicals
• C. High cost of glucosp 6-P
• D. Cells cannot take glucose 6-P

Answer 1

Answer: (D)

Cells cannot take glucose 6-P

Glucose solution is given intravenously for an instant source of energy. Glucose-6-phosphate is formed after phosphorylation of glucose. It cannot enter the cell directly and hence, glucose--phosphate is not given intravenously. Glucose can easily enter the cell and then phosphorylated to generate energy.

So, the correct answer is 'Cells cannot take glucose 6-P'.