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Question

Cosmids are ______


A

Naturally occurring vector

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B

Vector constructed using plasmid DNA and cos site of Lambda phage DNA

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C

Plasmid DNA with RNA

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D

None of the above

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Solution

The correct option is B

Vector constructed using plasmid DNA and cos site of Lambda phage DNA


Cosmids can be used to clone DNA fragments up to 45 kb in length. A cosmid is a type of hybrid plasmid that contains a Lambda phage cos sequence. The DNA sequences of Cosmids (cos sites + plasmid = cosmids) are originally from the lambda phage. They are often used as a cloning vector in genetic engineering


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