Question

Coupling reaction between $RMgX$ and $R^{\prime }-X$ takes place to give $R-R^{\prime }$ in the presence of which of the following reagents?

• A. $R^{\prime }-OTs$
• B. $Co{Cl}_2$
• C. $Mn{Cl}_2$
• D. All

Answer 1

Answer: (D)

All

In the presence of metal catalysts, however, Grignard reagents participate in $C-C$ coupling reactions. The coupling of alkyl halides with alkyl Grignard reagents, can be performed with a variety of nickel$\left(II\right)$ or palladium$\left(II\right)$ catalysts. Additionally $CoC{l}_2$ and $MnC{l}_2$ can also react as catalyst.