2
Question
Cross bridges of sarcomere in skeletal muscle are made up of
Cross bridges of sarcomere in skeletal muscle are made up of
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Solution
The correct option is B Myosin
- Active sites for myosin (Thick filament) are present on actin which are masked by troponin in resting state. when Ca++ level increases it leads to the binding of calcium with a subunit of troponin on actin(thin) filaments and thereby remove the masking of active sites for myosin.
- Utilizing the energy from ATP hydrolysis, the myosin head now binds to the exposed active sites on actin to form a cross bridge. thus myosin forms cross bridges.
- This pulls the attached actin filaments towards the centre of ‘A’ band.
- The ‘Z’ line attached to these actins are also pulled inwards thereby causing a shortening of the sarcomere, i.e., contraction.
- Hence cross bridges of sarcomere in skeletal muscle are made up of myosin.
- So, the correct answer is 'Myosin'.
- Active sites for myosin (Thick filament) are present on actin which are masked by troponin in resting state. when Ca++ level increases it leads to the binding of calcium with a subunit of troponin on actin(thin) filaments and thereby remove the masking of active sites for myosin.
- Utilizing the energy from ATP hydrolysis, the myosin head now binds to the exposed active sites on actin to form a cross bridge. thus myosin forms cross bridges.
- This pulls the attached actin filaments towards the centre of ‘A’ band.
- The ‘Z’ line attached to these actins are also pulled inwards thereby causing a shortening of the sarcomere, i.e., contraction.
- Hence cross bridges of sarcomere in skeletal muscle are made up of myosin.
- So, the correct answer is 'Myosin'.
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