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Question

Cry protein is an insecticidal protein which is produced by

A
Lactobacillus
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B
Bacillus thuringiensis
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C
Mycobacterium
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D
Mycoplasma
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Solution

The correct option is B Bacillus thuringiensis
Bacillus thuringiensis (Bt) is a gram-positive bacterium that produces crystals during sporulation. These crystals are Cry proteins which are potent and highly specific insecticides. Once ingested by the specific host, these crystals dissolve in the alkaline conditions of the gut thereby activating the protoxins. The active toxins then bind to receptors on midgut epithelial cells, become inserted into the plasma membrane where they form pores leading to cell death through osmotic lysis. This special feature of Bt toxin was explored in genetic engineering to produce bioinsecticidal Bt crop plants, e.g., Bt cotton, Bt brinjal etc.
Thus, the correct answer is option B.

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