Question

Curare acts on the same receptors as acetylcholine but does not cause the effect of acetylcholine, nor is it easily decomposed or cleaved by cholinesterases. What is the effect of an injection of curare into a person?
I. Epileptic seizures
II. Muscle relaxation
III. Suffocation

• A. I only
• B. II only
• C. III only
• D. I and II
• E. II and III

Answer 1

The correct option is E II and III

• Acetylcholine normally acts to stimulate muscle contraction; hence, competition at the neuromuscular junction by curare prevents nerve impulses from activating skeletal muscles.
• The major outcome of that competitive activity is profound relaxation (comparable only to that produced by spinal anaesthesia) and suffocation. Hence, Curare acts on the same receptors as acetylcholine but does not cause the effect of acetylcholine, nor is it easily decomposed or cleaved by cholinesterases. What is the effect of an injection of curare into a person is muscle relaxation and suffocation

So, the correct answer is 'II and III'.