Question

Cyclosporin A is a microbial product used as ____i____ obtained from a ______ii_______ named _____iii_______.

• A. i - cholesterol lowering agent, ii - bacterium, iii - Clostridium butylicum
• B. i - immunosuppresant, ii - fungus, iii - Trichoderma polysporum
• C. i - immunosuppresant, ii - yeast, iii - Monascus purpureus
• D. i - cholesterol lowering agent, ii - fungus, iii - Aspergillus niger

Answer 1

The correct option is B i - immunosuppresant, ii - fungus, iii - Trichoderma polysporum

Cyclosporin A is a microbial product produced by fungus Trichoderma polysporum, and used as an immunosuppressive agent in organ transplant patients. This helps them to suppress the activity of the immune system and ensures that the new organ is not rejected by the recipient.

Statins are produced by Monascus purpureus, a yeast. It helps in lowering the blood cholesterol levels by inhibiting cholesterol synthesis in the body.

Along with the chemicals used to treat diseases, microbes are also used to produce various organic acids such as citric acid (produced by Aspergillus niger), butyric acid (produced by Clostridium butylicum), etc.