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Question

Cyclosporin A, used as an immune suppressive agent is obtained from:

A
Bacterium Bacillus subtilis
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B
Fungus Trichoderma polysporum
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C
Fungus Plasmopara viticola
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D
Both a and b
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Solution

The correct option is B Fungus Trichoderma polysporum

Cyclosporin A is obtained from fermentative activity of fungus – Trichoderma polysporum. It has antifungal, anti-inflammatory and immune suppressive properties. Its major mode of action is inhibition of the production of cytokines involved in the regulation of T-cell activation and therefore, prevents rejection.


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