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Question

Cytotoxic T-cells are similar to natural killler cells in secretion of

A
Interferons
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B
Lysozymes
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C
Perforins
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D
Prostaglandins
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Solution

The correct option is C Perforins
  • Perforin is a pore-forming cytolytic protein found in the granules of cytotoxic T lymphocytes (CTL) and Natural Killer cells (NK cells).
  • Upon degranulation, perforin binds to the target cell's plasma membrane, and oligomerises in a Ca2+ dependent manner to form pores on the target cell.
  • Hence, Cytotoxic T-cells are similar to natural killer cells in the secretion of Perforins.
  • So, the correct answer is 'Perforins'.

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