Question

Deficiency of the adrenal cortex activity leads to

• A. Cushing disease
• B. Conn's syndrome
• C. Addison's disease
• D. Simmond's disease

Answer 1

The correct option is C Addison's disease

A. Cushing disease occurs due to hypersecretion of cortisol which is a glucocorticoid hormone secreted from adrenal cortex.

B. Conn's syndrome is caused due to hypersecretion of aldosterone which is a mineralocorticoid secreted from adrenal cortex.

C. Addison's disease is caused due to hyposecretion of steroid hormones from adrenal glands. The steroid hormones are cortisol and aldosterone which are secreted from adrenal cortex.

D. Simmonds's disease is a pituitary disorder caused due to destruction of anterior or posterior part of pituitary gland.

Hence, deficiency of adrenal cortex leads to 'Addison's disease'.

So, the correct answer is 'Addison's disease'.