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Question
Deficiency of Vitamin K will make blood clotting difficult because it is essential for
Deficiency of Vitamin K will make blood clotting difficult because it is essential for
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Solution
The correct option is C Prothrombin synthesis
Vitamin K serves as an essential cofactor for a carboxylase that catalyzes carboxylation of glutamic acid residues on vitamin K-dependent proteins. The carboxylation of the proteins results in the formation of prothrombin. The key vitamin K-dependent proteins includes coagulation proteins like factors II (prothrombin), VII, IX and X; anticoagulation proteins like proteins C, S and Z; other bone proteins osteocalcin and matrix-Gla protein, and certain ribosomal proteins. The coagulation proteins are activated by vitamin K and hence, the process of blood clotting is initiated by vitamin K. Deficiency of this vitamin may result in no blood clotting. Thus, the correct answer is option C.
Vitamin K serves as an essential cofactor for a carboxylase that catalyzes carboxylation of glutamic acid residues on vitamin K-dependent proteins. The carboxylation of the proteins results in the formation of prothrombin. The key vitamin K-dependent proteins includes coagulation proteins like factors II (prothrombin), VII, IX and X; anticoagulation proteins like proteins C, S and Z; other bone proteins osteocalcin and matrix-Gla protein, and certain ribosomal proteins. The coagulation proteins are activated by vitamin K and hence, the process of blood clotting is initiated by vitamin K. Deficiency of this vitamin may result in no blood clotting.
Thus, the correct answer is option C.
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