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Define Chromatin Fibres.

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this is not the direct definition but it's a small articles about chromatin fibre. Please go through this carefully.

chromatin fibres consist of discrete particles called nucleosomes which generate a bead-like structure. The thread (string) is made up of the DNA molecules; wound around the beads but does not pass through the beads.

The nucleosome is the basic structural unit of chromatin fibre; it consists of DNA wound around an “octamer” of histone proteins. A bacterial enzyme, micro-coccal nuclease, has the ability to cut DNA between nucleosomes. However, this enzyme cannot cleave the DNA wound round the histone octamer.

Individual nucleosomes, therefore, can be obtained following digestion of chromatin with micro-coccal nuclease. The stretch of DNA) between two nucleosomes (this DNA is digested by micro-coccal nuclease) is called linker DNA or spacer DNA.


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