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Question

Describe the role of haemoglobin in transport of oxygen and carbon dioxide in the body?

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Solution

Transport of Oxygen

  • Oxygen binds with haemoglobin to form oxyhaemoglobin.

  • 1 molecule of haemoglobin carries 4 molecules of oxygen.

  • Formation of oxyhaemoglobin depends upon − pO2, pCO2, pH, temperature

  • In alveoli − pO2 (high), pCO2 (low), pH (high) temperature (low)
    Hence, oxyhaemoglobin forms.

  • In tissues − pO2 (low), pCO2 (high), pH (low) temperature (high)
    Hence, oxyhaemoglobin dissociates.

    Transport of Carbon Dioxide

  • CO2 is carried as carbamino-haemoglobin by blood.

  • When pCO2 (high), pO2 (low) − binding of CO2 occurs (as in tissues)

  • When pCO2 (low), pO2 (high) − dissociation of CO2 occurs (as in alveoli)

  • CO2 is bound with haemoglobin in tissue and dissociates in alveoli where it is released.


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