Question

Detoxification of lipid soluble drugs and other harmful compounds in ER is carried out by ..........

• A. Cytochrome $a_1-a_3$
• B. Cytochrome $c$
• C. Cytochrome $bf$
• D. Cytochrome $P_{450}$

Answer 1

The correct option is D Cytochrome $P_{450}$

Detoxification of lipid-soluble drugs and other harmful compounds in ER is carried out by cytochrome P450 because cytochrome P450 are a group of oxygenase enzyme present in ER of the liver cell responsible for detoxification of a number of xenobiotics (foreign compound), drugs, toxins, products of endogenous metabolism inside our body, etc.

So the correct option is "Cytochrome $P_{450}$".