The correct option is A Which is also involved in synthesis of steroid hormone.
Detoxification of drugs and many poisons is done by liver cells in the human body due to presence of an organelles known as SER. SER is also involved in steroid synthesis. Nucleus has close proximity with RER that has a ribosome attached to it. After RER, SER comes, so it is far away from the nucleus.Ribosomes are the smallest organelles of the cell.Ribosomes are protein factories and it is called as organelle within organelle. SER does not contain ribosomes.