Question

Developing vaccines for AIDS is very difficult. Give reasons.​

Answer 1

$AIDS$ is caused by the Human Immunodeficiency Virus$\left(HIV\right)$. Developing vaccine for $AIDS$ is very difficult due to the following reasons: ​ ​

• $HIV$ has a high capability to form different kinds of variants. ​ ​
• Some $HIV$-infected immune cells go into a dormant, or latent, state and does not make new virus. $HIV$ can hide in this “ latent reservoir ” for a long time.​ ​
• $HIV$ uses the genetic material of $T-$ helper cells by attaching its viral genetic material with the genetic material of the $T-$helper cell to produce more viral products. So, vaccination against the virus destroys our own $T-$ helper cells consisting of the viral genetic material.​ ​