Question

Dialysis not a sustainable option for patients because-

• A. Lies at the junction of distal tubule and against the afferent (efferent) arteriole
• B. Arteriole walls have juxtaglomerular cells, enlarged smooth muscle cells, Have secretory granules containing renin, Act as mechanoreceptors
• C. Macula densa-Function as chemoreceptors (sense concentrations of Na+, K+ and Cl-) and on sensing higher levels of these ions, release prostaglandins which suppress the granular cells from releasing renin.
• D. Mesangial cells, Have phagocytic and contractile properties, Influence capillary filtration

Answer 1

The correct option is C Macula densa-Function as chemoreceptors (sense concentrations of Na+, K+ and Cl-) and on sensing higher levels of these ions, release prostaglandins which suppress the granular cells from releasing renin.

Dialysis is done when the kidneys fail to function. A patient takes recourse to an artifical kidney to filter his blood of all urea deposits. Now, during ultra filtration in the glomerulous, apart from urea and water, many useful sodium , potassium ions too get filtered . The natural human kidney has a way to redo this loss by reabsorbing all the useful components of primary urine such as glucose, amino acids,vitamin C, Potassium, Calcium,Sodium, Chlorides and 75% of water thereby helping to maintian the proper pH level of the urine. This does not happen in an artificial kidney. Prolonged dialysis makes the patient become vulnerable to a host of diseases arising out of this imbalance and deficiency of ions. Hence, dialysis is not sustainable.