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Difference between hormone and enzyme in tabular form

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BASIS FOR COMAPRISION ENZYMES HORMONES
Nature All enzymes are protein (exception is ribozyme) Hormones are derivative of protein, amino acids, and steroids.
Molecular weight Higher molecular weight. Lower molecular weight.
Role Enzymes are the catalyst, which enhances the biochemical reactions. Hormones are the chemical messenger that provide signals to the cell for performing the particular function.
Carrier Enzymes act at the place where they are formed. Hormones are carried by the blood to different part of the body for giving signals to the cell.
Diffusibility Enzymes are non-diffusable through a cell membrane. Hormones are diffusable through the cell membrane.
Site of Action Enzymes perform their action on the site(place) where they are produced. Hormones perform their action to the different place from where they are produced and are carried by the blood.
Origin Enzymes are produced in exocrine glands. Hormones are produced in endocrine glands.
Factors affecting Enzymes perform in particular temperature, pH. No effect of pH or temperature or pH, but sometimes effected by external factors.
Specificity Enzymes are substrate specific i.e. depends on the substrate to perform the function. Hormones are target cell specific and depend on positive and negative feedback mechanism.
Metabolic activity Enzymes take part in metabolism. Hormones regulate the metabolic activity i.e. while giving signals to the cell for performing various body functions.
Effect of age Enzymes have no effect of age. Hormonal changes can be seen with age like puberty, menopause.
Dependency Enzymes start performing only when it get the message from hormone. Hormones do not depend on an enzyme.
Occurrence of Disease Comparatively fewer chances of occurrence of diseases, and are only due to insufficiency Hormonal disorders are very common, and even a single wrong message sent to the cell may give rise to life-long disease or disorders.
Utility Enzymes can be reutilized after their function as they are the catalyst and remain unchanged. Hormones cannot be reutilized once their function is over, they naturally get destroyed.
Examples Oxidoreductase,
Transferase,Hydrolase etc.
Insulin, Glucagon, Thyroid (T3, T4).

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