Question

Differentiate between chromosomal and gene mutation. How is frame-shift mutation different from point mutation?

Answer 1

Frame-shift mutation	Point mutation
Mispairing of DNA molecule causes the Frameshift mutations, changes in single base pair nucleotide sequence usually insertion or deletion results in these mutations.	Point mutations occur when a single nucleotide is replaced with another nucleotide base.
The whole information coded in the amino acid changes due to a Mutation occurs in the sequence of DNA molecule in a frameshift mutation.	The mutation occurs in the sequence of a DNA molecule.

Gene mutation	Chromosomal mutation
It is a change in nucleotide sequence, in a particular gene.	It is a change in several genes, in the chromosome.
Gene mutation is an only slight structural alteration.	Chromosomal mutations are either numerical or structural changes in the entire DNA strand.