Differentiate between competitive and non competitive inhibitors.

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Solution

Competitive inhibitors Non-competitive inhibitors
Its structure is similar to that of substrate. Its structure is entirely different.
It attaches at the active site of an enzyme. It attaches at a point other than active site.
The reaction can be reversed by increasing the substrate concentration.
The reaction cannot be reversed by increasing the substrate concentration.

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Q. Differentiate the action of competitive, uncompetitive and non-competitive inhibitors.

Q. Discuss competitive and non-competitive enzyme inhibitors.

Which of the following statements is not true about enzyme inhibitors?
(a) Inhibit the catalytic activity of the enzyme
(b) Prevent the binding of substrate
(c) Generally a strong covalent bond is formed between an inhibitor and an enzyme
(d) Inhibitors can be competitive or non-competitive

Q. In the presence of a non competitive inhibitor

Non-competitive inhibitor changes the active site of enzyme after binding at:

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Competitive inhibitors	Non-competitive inhibitors
Its structure is similar to that of substrate.	Its structure is entirely different.
It attaches at the active site of an enzyme.	It attaches at a point other than active site.
The reaction can be reversed by increasing the substrate concentration.	The reaction cannot be reversed by increasing the substrate concentration.