Question

Differentiate between rough endoplasmic and smooth endoplasmic reticulum.

Answer 1

Rough endoplasmic reticulum:

1. It is one type of endoplasmic reticulum that is primarily concerned with the synthesis, folding, and modification of proteins.

Smooth endoplasmic reticulum:

1. It is one type of endoplasmic reticulum that is involved in the metabolism of lipids and glycogen.

Difference between rough endoplasmic and smooth endoplasmic reticulum:

Rough endoplasmic reticulum	Smooth endoplasmic reticulum
1. It contains flattened sacs which are called cisternae and a few tubules.	1. It contains a few vesicles and tubules.
2. It is found near the cytoplasm.	2. It is found near the cell membrane.
3. It possesses ribosomes on its outer surface.	3. It does not contain ribosomes.
4. It synthesizes proteins and enzymes.	4. It synthesizes glycogen, lipids, and steroids.
5. It helps in the formation of lysosomes.	5. It gives rise to Spherosomes / Oleosomes.