Differentiate between the following:
Exophthalmic goitre and Iodine deficiency goitre

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Solution

(1) Exophthalmic goitre is the clinical syndrome due to hypersecretion of thyroid secretion. It is also known as Grave's disease.
(2) Iodine deficiency goitre is a disorder characterized by enlargement of the thyroid gland which brings about swelling in the front part of the neck region, such a condition is known as goitre.
Exophthalmic goitre
Iodine deficiency goitre
1. The hyperthyroidism of thyroid gland results in exophthalmic goitre due to excessive secretion of thyroxine hormone. 1. The iodine deficiency in the diet produces thyroid enlargement accompanied by cretinism in childhood and myxedema in adults.
2. It is characterized by protrusion of eye ball, increased basal metabolic rate, heat intolerance, hair loss, restlessness, tremors, nervousness, insomnia, weight loss, excessive sweating, muscle weakness etc. 2. This type of goitre is characterized by reduction of oxidation of food, less heat production, slow heart rate and gain in body weight . The person shows a puffy appearance (edema).

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Exophthalmic goitre	Iodine deficiency goitre
1. The hyperthyroidism of thyroid gland results in exophthalmic goitre due to excessive secretion of thyroxine hormone.	1. The iodine deficiency in the diet produces thyroid enlargement accompanied by cretinism in childhood and myxedema in adults.
2. It is characterized by protrusion of eye ball, increased basal metabolic rate, heat intolerance, hair loss, restlessness, tremors, nervousness, insomnia, weight loss, excessive sweating, muscle weakness etc.	2. This type of goitre is characterized by reduction of oxidation of food, less heat production, slow heart rate and gain in body weight . The person shows a puffy appearance (edema).