Question

Diphtheria toxin:

• A. Inhibits protein synthesis that results in release of incomplete polypeptide chains from the ribosome.
• B. Activates translocase.
• C. Prevents release factor from recognizing termination signals.
• D. Attacks the RNA of the large subunit

Answer 1

The correct option is C Prevents release factor from recognizing termination signals.

Diphtheria toxin (DT) is an extracellular protein of Corynebacterium diphtheriae that inhibits protein synthesis, which results the release of incomplete polypeptide chains from the ribosome and kills susceptible cells.