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Question

Discuss the role of enzyme DNA ligase in DNA replication.

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Solution

DNA ligase is a specific type of enzyme, a ligase, that facilitates the joining of DNA strands together by catalyzing the formation of a phosphodiester bond. DNA ligase has a different role in DNA replication :
  1. DNA ligase is a specific type of enzyme, a ligase, (EC 6.5.1.1) that facilitates the joining of DNA strands together by catalyzing the formation of a phosphodiester bond.
  2. DNA ligase is used in both DNA repair and DNA replication (see Mammalian ligases).

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