Apoenzyme | Cofactor |
This is the protein part which gets attached to the enzyme. | This is the non-protein part of the enzyme. |
Apoenzyme is specific for the enzyme | The cofactor may get attached to the different type of enzymes belonging to the same group. |
This is heat sensitive. | This is heat stable. |
Apoenzyme has catalytic activity. | The cofactors are involved in the removal of the product. |