Question

Division of centromere followed by separation of sister chromatids is observed during

• A. Metaphase
• B. Prophase
• C. Anaphase
• D. Telophase

Answer 1

The correct option is C

Anaphase

The correct option is C

Explanation of the correct option :

1. Anaphase is a mitotic cell division phase that comes after metaphase.
2. Here, the centromeres split and the chromatids separate and move to opposite poles.

Explanation of the incorrect option :

Option A:

Metaphase:

1. At this stage, the microtubules start pulling the chromosomes with equal force and the chromosome ends up in the middle of the cell.
2. This region is known as the metaphase plate. Thus, each cell gets an entire functioning genome

Option A:

Prophase:

1. It is the first stage of Mitosis.
2. The completion of prophase is characterised by the initiation of the assembly of the mitotic spindle, the microtubules and the proteinaceous components of cytoplasm that help in the process.

Option D:

Anaphase:

1. The chromosomes that cluster at the two poles start coalescing into an undifferentiated mass, as the nuclear envelope starts forming around it.
2. The nucleolus, Golgi bodies and ER complex, which had disappeared after prophase start to reappear.

Final answer: Division of centromere followed by separation of sister chromatids is observed during anaphase.