DNA is a polymer of nucleotides which are linked to each other by 3-5 phosphodiester bond. To prevent polymerisation of nucleotides, which of the following modifications would you choose?
A
Replace purines with pyrimidines.
No worries! We‘ve got your back. Try BYJU‘S free classes today!
B
Remove/Replace 3 OH group in deoxyribose.
Right on! Give the BNAT exam to get a 100% scholarship for BYJUS courses
C
Remove/Replace 2 OH group with some other group in deoxyribose.
No worries! We‘ve got your back. Try BYJU‘S free classes today!
D
Both (b) and (c).
No worries! We‘ve got your back. Try BYJU‘S free classes today!
Open in App
Solution
The correct option is B Remove/Replace 3 OH group in deoxyribose. If 3 OH group is removed/replaced in deoxyribose, there will be no formation of pliosphodiester bonds and hence polymerisation of nucleotides will be prevented.