Question

Do you know any step in the TCA cycle where there is substrate level phosphorylation. Which one?

Answer 1

Substrate level phosphorylation:

Substrate level phosphorylation is the process of formation of ATP by the transfer of phosphate groups from a substrate to ADP, rather from ADP and Pi (organic phosphate).

Substrate level phosphorylation in the TCA cycle:

$\bullet$ Conversion of Succinyl CoA to succinic acid is the substrate level phosphorylation that takes place in the TCA cycle.

$\bullet$ In this reaction, GTP is formed from GDP and Pi after the removal of CoA from succinyl-CoA