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Down's Syndrome

Down's syndro...

Question

Down's syndrome is-

A

44 + X X Y

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B

45 + X X

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C

44 + X 0

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D

44 + X Y Y

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Solution

The correct option is B $45 + X X$
Down's syndrome is a genetic disorder where there is an extra 21st chromosome. It is also hence known as trisomy-21 and is represented as 45+XY or 45+XX.
So the correct option is '45+XX'.

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Q. Match list-I with list-II and select the correct answer using the code given below:
List-I (Syndrome) List-II (Chromosomal abnormality)
(1) Patau's syndrome (A) 44 + XXY = 47

(2) Klinefelter's syndrome (B) 44 + XO = 45
(3) Down's syndrome (C) 46 + 1 = 47, (trisomy 13)

(4) Turner's syndrome (D) 46 + 1 = 47, (trisomy 21)

Filling the blanks based on the given relationship.

a. 44+X:Turner syndrome: :44+XXY:- ..............

b. 3:1 Monohybrid: : 9:3:3:1 : .............

c. Women : Turner syndrome : : Men : .......

Q. Match the syndromes and chromosomal abnormalities given in columns.

	List I - Syndrome		List II - Chromosomal abnormalities
A	Klinefelter syndrome	p	Trisomy 13
B	Turner's syndrome	q	Trisomy 18
C	Super female	r	44+XXY
D	Patau's syndrome	s	44+XXX
		t	44+XO

Q. Which of the following is correct match?

I	II	III
A) Thalassemia	a) XO	i) Flat nose, simian crease
B) Down's syndrome	b) $42$ AA $+$ XY	ii) Webbing of neck
C) Turner's syndrome	c) $44$ AA $+$ XXX	iii) Anaemia, jaundice
D) Klinefelter's syndrome	d) $44$ AA $+$ XXY	iv) Tall thin eunuchoid

Q. Criminal syndrome is due to 44 + ____.

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