The correct option is A Aneuploidy
Aneuploidy is changes in chromosome number by additions or deletions of less than a whole set. Presence of multiple numbers of complete haploid chromosomal sets is polyploidy. Presence of 3 complete haploid chromosomal sets is triploidy (3n) and presence of one complete haploid chromosomal sets is monoploidy (n). Polytene chromosomes are giant chromosomes having many parallel DNA duplexes as result of the endo-reduplication and the synapsis of homologues without cell division. Down's syndrome is caused by presence of chromosome 21 in three copies and thus, is an autosomal aneuploidy. Correct answer is option A.