Question

Down's Syndrome is caused by trisomy of chromosome number 21. True or False?

• A. True
• B. False

Answer 1

The correct option is A

True

The chromosomal disorders are caused due to absence or excess or abnormal arrangement of one or more chromosomes. Failure of segregation of chromatids during cell division cycle results in the gain or loss of a chromosome(s), called aneuploidy. For example, Down's syndrome results in the gain of extra copy of chromosome number 21, i.e., the baby will have three copies of this chromosome (also called trisomy of 21st chromosome).