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Question

During carbohydrate metabolism, NADH is produced in which of the following locations?
I. Cytosol
II. Mitochondrial matrix
III. Nucleus.

A
I only
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B
II only
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C
I and II only
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D
I, II and III
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Solution

The correct option is B I and II only
In the cytoplasm, one glucose molecule breaks down into two pyruvate molecules, and creates two NADH molecules by glycolysis. Transformation of one pyruvate from cytosol to one acetyl CoA produces one NADH molecule in the mitochondrial matrix. During each turn of Krebs cycle, each acetyl CoA is systematically processed through the cycle and produces three NADH molecules.
So, the correct option is 'I and II only'.

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