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Question

During CO2 transport, HCO3 diffuses from erythrocytes to plasma and in turn upsets the ionic balance momentarily. In order to keep the ionic balance, an equal number of Cl pass into the erythrocytes from plasma. The process is known as

A
Hamburger phenomenon
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B
Bicarbonate shift
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C
Carbonation
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D
Bohr's effect
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Solution

The correct option is C Hamburger phenomenon
About 70% of CO2 is converted to bicarbonate ions (HCO3) and transported in plasma. CO2 diffuses into RBCs, combines with-water and forms carbonic acid {H2CO3). H2CO3 being unstable quickly dissociates Into H+ and HCO3. HCO3 ions are quite diffusible. Therefore, HCO3 diffuses from RBCs into the plasma. To maintain the ionic balance CI ions move from the plasma into the RBCs. This exchange is called chloride shift or Hamburger's phenomenon.
So, the correct answer is 'Hamburger phenomenon'.

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